https://scarmilab.org/publications/2026-02-24T11:21:52+00:00weekly0.6https://scarmilab.org/lab-members/https://scarmilab.org/wp-content/uploads/2026/02/ethel.jpegEthelhttps://scarmilab.org/wp-content/uploads/2026/02/gilat.jpegGilathttps://scarmilab.org/wp-content/uploads/2022/11/aric-1.jpgaric-12026-02-02T07:31:59+00:00weekly0.6https://scarmilab.org/shai-carmi/https://scarmilab.org/wp-content/uploads/2025/04/me47.jpghttps://scarmilab.org/wp-content/uploads/2015/12/me11.jpgSChttps://scarmilab.org/wp-content/uploads/2015/12/me2.jpgSC2025-04-26T06:54:14+00:00weekly0.6https://scarmilab.org/talks-teaching-materials/2024-11-27T14:03:37+00:00weekly0.6https://scarmilab.org/open-positions/2022-11-28T08:14:55+00:00weekly0.6https://scarmilab.org/contact/https://scarmilab.org/wp-content/uploads/2016/06/hadassah.jpgHadassahhttps://scarmilab.org/wp-content/uploads/2015/08/hadassah_university_hospital_ein-karem2.jpgHadassah_University_Hospital,_Ein-karem2https://commons.wikimedia.org/wiki/File:Hadassah_University_Hospital,_Ein-karem2.JPGhttps://scarmilab.org/wp-content/uploads/2014/08/hadassah_university_hospital_ein-karem2.jpgHadassah_University_Hospital,_Ein-karem2https://scarmilab.org/wp-content/uploads/2014/08/dsc_2769.jpgDSC_2769https://scarmilab.org/wp-content/uploads/2014/08/hadassahcampusphoto.jpgHadassahCampusPhoto2021-10-12T06:47:52+00:00weekly0.6https://scarmilab.org/lab-members-old/2020-02-11T10:22:06+00:00weekly0.6https://scarmilab.org/embryo-screening-qanda/2019-11-24T12:44:37+00:00weekly0.6https://scarmilab.org/ashkenazi-jewish-genetics/https://scarmilab.org/wp-content/uploads/2014/08/ibd_decay_curve.pngIBD_decay_curveThe pattern of lengths of shared segments in Ashkenazi Jews (AJ) cannot be explained by a constant population size, but is very well fitted into a population undergoing a severe bottleneck (decrease in the population size) followed by rapid expansion. From Carmi et al., Nat. Commun., 2014.https://scarmilab.org/wp-content/uploads/2014/08/figure4.pngDemographyA reconstruction of the Ashkenazi Jewish and European demographic history using DNA sequence data. (AJ: Ashkenazi Jews; FL: Flemish from Belgium). The upper part shows the reconstruction of the ancient history of these populations, while the lower part shows the recent AJ history. Horizontal arrows correspond to effective population size. The wide arrow represents a migration event. The ancient reduction in population size on the right side likely corresponds to an Out-Of-Africa event and the formation of the Middle-Eastern population. This was followed by a split of the European population, members of which later migrated into the Ashkenazi population. From Carmi et al., Nat. Commun., 2014.2018-05-21T06:16:50+00:00weekly0.6https://scarmilab.org/population-genetics/https://scarmilab.org/wp-content/uploads/2015/07/timeinference.pngAdmixtre time InferenceSimulation results for the inference of the time of admixture between two populations. We first recorded, for each individual, the proportion of the genomes coming from each ancestral population. We then used our newly developed expression for the distribution of ancestry proportions to infer the admixture time. The inferred time is shown vs the true simulated time.https://scarmilab.org/wp-content/uploads/2015/07/smc_joint_density.pngJoint densityThe joint density of the time to the common ancestor (t1 and t2) and two genomic loci separated by distance rho. Each panel shows the difference between the densities under the complete model (of the coalescent with recombination) to one of the Markovian approximates, SMC or SMC'. From Wilton et al., Genetics, 2015.2018-05-21T05:59:04+00:00weekly0.6https://scarmilab.org/haplotype-sharing/https://scarmilab.org/wp-content/uploads/2014/08/illustration.pngIllustrationAn illustration of the sample history leading to sharing of a genomic segment. The ancestral chromosome (red) is broken by recombination at each generation. However, if the common ancestor of A and B lived recently, the shared segment will remain long.https://scarmilab.org/wp-content/uploads/2014/08/numseg.pngNumSegFrom Carmi et al., Theor. Popul. Biol., 20142018-05-21T05:57:40+00:00weekly0.6https://scarmilab.org/publications_list/2018-01-16T19:43:32+00:00weekly0.6https://scarmilab.org/tagc/https://scarmilab.org/wp-content/uploads/2014/08/tagc_dreidel.jpg2017-03-05T09:53:14+00:00weekly0.6https://scarmilab.orgdaily1.02026-02-24T11:21:52+00:00